Sir Keir Starmer was asked at Prime Minister's Questions about his decision to award a peerage to Lord Doyle.
Juliette Bryant has called on the Palace to "act" on revelations about Andrew's relationship with Epstein.
Gordon Brown said police should "urgently" re-examine their investigation into Epstein's victims possibly being trafficked in and out of the UK.
The victims, aged 12 and 13, are in a stable condition in hospital after the stabbing at a school in north-west London.
Police are investigating more than five people who may have facilitated Al Fayed in his alleged abuse.